Bioactive Small Molecules
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Filtered Search Results
Medchemexpress LLC Katacalcin (TFA) | 99.6% | 2550.62 | 100 MG
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Katacalcin TFA (PDN 21 TFA) is a potent plasma calcium-lowering peptide from the calcitonin family. It induces a rapid, short-lived decrease in blood calcium and phosphate by promoting bone incorporation. This peptide, encoded by the calc-1 gene alongside calcitonin and procalcitonin NH2-terminal cleavage peptide, effectively inhibits fMLP-induced chemotaxis and deactivates CD14+ peripheral blood mononuclear cell chemotaxis toward various attractants.
- Potent plasma calcium-lowering peptide
- Belongs to the calcitonin family
- Decreases blood calcium and phosphate levels
- Promotes incorporation into bones
- Inhibits fMLP-induced chemotaxis
- Deactivates CD14+ peripheral blood mononuclear cell chemotaxis
- Regulates CD14+ PBMC migration via protein kinase A-dependent cAMP pathways
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Medchemexpress LLC Angiotensin III, human, mouse | 13602-53-4 | 98.26% | 931.09 | 25 MG
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Angiotensin III, human, mouse is a heptapeptide that functions as an endogenous angiotensin type 2 receptor (AT2R) agonist. It exhibits IC50s of 0.648 nM for AT2R and 21.1 nM for AT1R. This compound is intended for research use only.
- Heptapeptide
- Acts as an endogenous angiotensin type 2 receptor (AT2R) agonist
- Exhibits IC50s of 0.648 nM for AT2R
- Exhibits IC50s of 21.1 nM for AT1R
- Increases urine sodium excretion in SD rats
- Increases fractional excretion of sodium in SD rats
- Increases fractional excretion of lithium in SD rats
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Medchemexpress LLC Cholesterol hemisuccinate Tris salt | 102601-49-0 | 98.0% | 607.86 | 10MG
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Cholesterol hemisuccinate Tris salt is a chemical reagent intended for research use only and is not for human use.
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Medchemexpress LLC 9-cis-Retinoic acid (Alitretinoin) | 5300-03-8 | C20H28O2 | 100 MG
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9-cis-Retinoic acid, also known as Alitretinoin, is a vitamin A derivative and a potent RAR/RXR agonist. It induces apoptosis, regulates the cell cycle, and possesses anticancer, anti-inflammatory, and neuroprotection activities.
- Potent RAR/RXR agonist
- Induces apoptosis
- Regulates the cell cycle
- Exhibits anticancer activity
- Offers anti-inflammatory effects
- Provides neuroprotection
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Medchemexpress LLC ATP synthase inhibitor 2 | 2814540-76-4 | C21H22N2O3S | 5 MG
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This product is an ATP synthase inhibitor, specifically targeting *Pseudomonas aeruginosa*. It demonstrates complete inhibition of ATP synthesis activity in this bacterium at a concentration of 128 μg/mL.
- Inhibits ATP synthase.
- Specifically targets *Pseudomonas aeruginosa*.
- Achieves complete inhibition of ATP synthesis at 128 μg/mL.
- Available in solid form, white to off-white in color.
- Has high purity.
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Cayman Chemical AT-130, Purity: ≥98%, CAS: 211364-06-6, 5 mg
An antiviral agent; a non-nucleoside inhibitor of HBV replication in wild-type and rtL180M, rtM204I, and rtL180M + rtL204V lamivudine-resistant strains of HBV (IC50s = 2.4, 1.6, 5.1, and 1.3 µM, respectively); inhibits viral DNA synthesis in HBV-infected HepAD38 cells (EC50 = 0.13 µM)
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Cayman Chemical TA-01, Purity: ≥98%, CAS: 1784751-18-3, 1 mg
An inducer of cardiomyocyte differentiation; increases expression of the cardiomyocyte marker NKX2-5 by 2.2-fold and decreases expression of mesoderm markers and the pre-cardiac marker Isl-1 in HES-3 NKX2-5eGFP/w cells at <5 μM; inhibits CK1ε and CK1Δ and reduces expression of Wnt/β-catenin signaling pathway members
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Medchemexpress LLC 4,4'-octanamidostilbene-2,2'-disulfonate | 5970-15-0 | >98.0% | 25 MG
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OADS (4,4'-octanamidostilbene-2,2'-disulfonate) is a small-molecule inhibitor of the ClC-ec1 Cl-/H+ antiporter used as a biochemical and structural research reagent.
- Inhibits ClC-ec1 with low micromolar affinity.
- Designed disulfonated stilbene with octanamide side chains.
- CAS number 5970-15-0.
- Purity greater than 98%.
- Molecular weight 666.76 g/mol; formula C30H40N2Na2O8S2.
- For research use only; not for human or veterinary use.
- Typical package size 25 MG.
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Medchemexpress LLC Bz-rA Phosphoramidite | 104992-55-4 | 988.19 | 1 ML
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Bz-rA Phosphoramidite, also known as DMT-2'O-TBDMS-rA(bz) Phosphoramidite, is a phosphoramidite containing 5' DMT and the nucleoside adenosine (A) with Benzoyl (Bz) base protection. It is used in oligonucleotide synthesis and intended for research use only.
- A 2'-O-protected ribonucleoside phosphoramidite
- Used in oligonucleotide synthesis
- Suitable for laboratory chemicals and manufacture of substances
- Can be used in the synthesis of 2'-O-guanidinopropyl-modified nucleoside phosphoramidites
- For research use only and for experienced personnel
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TARGETMOL CHEMICALS INC UNC-2170 5MG
Also available in 1 mg 2 mg 10 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. UNC-2170 (UNC2170 Maleate) is the methyl-lysine binding protein 53BP1 ligand. purity: 98%
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Cayman Chemical U-47109, Purity: ≥98%, CAS: 67579-13-9, 1 mg
An analytical reference standard categorized as an opioid; intended for research and forensic applications
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![eMolecules 55256-49-0 | Sterigmatin | Apollo Scientific | MFCD01725644 | 310.261 | C17H10O6 | 74.000 | Oc1cccc2oc3cc4O[C@H]5OC=C[C@H]5c4c(O)c3c(=O)c12 | 1mg | 562465667](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502153105.JPG-250.jpg)
eMolecules 55256-49-0 | Sterigmatin | Apollo Scientific | MFCD01725644 | 310.261 | C17H10O6 | 74.000 | Oc1cccc2oc3cc4O[C@H]5OC=C[C@H]5c4c(O)c3c(=O)c12 | 1mg | 562465667
Sterigmatin | Apollo Scientific | 55256-49-0 | MFCD01725644 | 310.261 | C17H10O6 | 74.000 | Oc1cccc2oc3cc4O[C@H]5OC=C[C@H]5c4c(O)c3c(=O)c12 | 1mg | 562465667
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Cayman Chemical RN-486, Purity: ≥98%, CAS: 1242156-23-5, 10 mg
A selective BTK inhibitor (Kds = 0.31 nM; IC50 = 4 nM); produces anti-inflammatory and bone-protective effects in mouse collagen-induced arthritis and rat adjuvant-induced arthritis models
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Selleck Chemical LLC 2-C-Methylcytidine E6045-1G
2 -C-Methylcytidine (NM107) is a potent and selective inhibitor of Chronic hepatitis C virus (HCV) NS5B polymerase with an EC50 of 1 85 M in wild-type replicon cells It also effectively inhibits foot-and-mouth disease virus(FMDV) replication with an EC50 of 6 4 M Therefore it is a potent antiviral that targets both viral and host factors making it a promising option for HCV therapy and a potential prophylactic or therapeutic agent against FMDV outbreaks
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Cayman Chemical DSRM-3716, Purity: ≥95%, CAS: 58142-99-7, 5 g
A SARM1 inhibitor (IC50 = 75 nM); decreases levels of cADPR and increases NAD+ levels in axotomized primary mouse DRG axons from 1.1-30 µM; prevents axonal degeneration in primary wild-type but not Sarm1-/- axotomized DRG axons
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